Enter the terms you wish to search for. Venkataraman, works on developing next generation fe exam review pdf for energy conversion and storage. Gierasch Winner of the Ralph F. Gierasch was awarded the Ralph F.
Hirschmann Award in Peptide Chemistry for her seminal contributions to peptide structure and function, peptide models for protein folding and function, and roles of peptide and protein aggregation in disease. The environment in a cell is extremely complex and challenging for the process of protein folding, leading to a need for a network of species that protect protein states that are susceptible to aggregation—the protein homeostasis network. We are working with colleagues and collaborators to understand the underlying mechanisms of protein homeostasis from the level of the molecular chaperone machines that act on protein clients to the coordinated action of the network in all of its complexity. We would love to witness and contribute to new discoveries related to these questions, both because of the fascinating basic science involved and because failures in these systems are implicated in a wide array of diseases, including neurodegenerative diseases. 615,000 NIH grant entitled, “Assembly and Function of Bacterial Chemotaxis Receptor Signaling Complexes. The goal of this project is to assemble native-like functional nanoarrays of chemotaxis receptor complexes and determine how the proteins change their structure and dynamics during signaling. Understanding signaling in this system may be useful for the development of novel antibiotics targeting similar signaling systems that are widespread in bacteria.
Larry Renna, Connor Boyle and others, report that they have developed a polymer-based system that can yield energy storage density more than two times higher than previous polymer systems. The twist in the story is that we thought that the distance between the lights in the string was the most important. It is important, but what is more important is the way that multiple strings and their lights are carefully arranged. It turns out that the processing solvent we used acts to arrange and regulate the architecture, so the azobenzene molecules attached to the polymer are arranged very neatly and compactly. It basically acts to ensure that there can be maximum packing density. His-Tag-Mediated Dimerization of Chemoreceptors Leads to Assembly of Functional Nanoarrays.
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